If you think Santana still has a problem with his eye and your vet can't help you- you will need to take him to a specialist. If he has an eye ulcer or scatch that is causing him pain, it can get very serious if left untreated. Did your regular vet take a look at his eye? There has to be some reason, Santana can't open his eyes- my guess is that it is painful.

I'm sending hugs, purrs and prayers for Santana. Give him a hug and kiss from Auntie Jay. :heart:

I had this same issue with my avatar kitty Monty, red rimmed eyes, keeping them closed in the show hall. Took him to my vet, he said allergies, not being happy with that answer I went to a specialist, 3 trips 4 meds and $500 later, I've come to the conclusion.......it's allergies.

My cat has had eye problems about since she was born and she is over a year old now. I had taken her to two vets with different types of treatments. There was a scratch and that was fixed, then the ulcer and all the different meds she was put on has never really gotten that eye open totally nor stopped it from tearing. And even though the vets treatment has not corrected the problem totally, they still charge you the next visit. If you ask me I think that if the problem isn't resolved at least by the second visit the other visits should be free. We are depending on the vets knowledge, they went to vet school we didn't. They should know the stuff for small animal problems. Considering, from what I have read many cats have eye problems, they should know how to combat the issue. It would be like the medical doctor, all people have appendix's every doctor knows what the symptoms are for what they call Hot when your having  an attack. All doctors know when to hospitalize you to get it operated on before it ruptures. Vets should know how to treat cats eyes to resolve the problems.

One problem I didn't see mentioned, unless I just missed it, is Entropian. With this problem the eyelids turn in and the eyelashes irritate the eyes. It can scratch the eye and cause problems. My Missy acted just like what yours does, she had surgery to correct it. My Sparky also has this problem and will be having surgery for it. Did your Vet put a dye in the eye and look at it with a special light and magnification? You can't see ulcers or abrasions otherwise. You may have to go to a specialist, eyes are nothing to mess with. Keeping them closed indicates pain, usually to light. Sorry you are having issues, poor little guy.